14-3-3ζ controls adipocyte progenitor cell cycle and differentiation via Gli3-dependent p27Kip expression
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ABSTRACT: 14-3-3 proteins facilitate cytoplasmic-nuclear shuttling of transcription factors.Adipocyte differentiation requires the function of critical transcription factors to drive the development of a mature adipocyte. The aim of the study was to investigate if 14-3-3ζ is required for the adipogenic transcriptional program. Examination of the transcriptome in siCon- and si14-3-3ζ-transfected 3T3-L1 cells undergoing differentiation at t=0, 24, and 48 hours.
ORGANISM(S): Mus musculus
SUBMITTER: Gareth Lim
PROVIDER: E-GEOD-60745 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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