MicroRNA expression signatures of imatinib-treated and non-treated gastrointestinal stromal tumors
Ontology highlight
ABSTRACT: We performed microRNA expression profiling in a series of fresh-frozen neoadjuvantly imatinib-treated and non-treated gastrointestinal stromal tumors (GIST), using a microarray approach. Significant differentially expressed microRNAs among imatinib-treated and non-treated groups were identified using SAM analysis. Agilent microarray platform with probes matching 903 human microRNAs was used to determine miRNA expression profiles in 34 GISTs (19 imatinib-treated and 15 non-treated). Re-analysis of GSE45901 for 17 imatinib-treated GISTs. To validate the microarray platform, the expression levels of selected microRNAs were evaluated using qRT-PCR.
ORGANISM(S): Homo sapiens
SUBMITTER: Pinar Akcakaya
PROVIDER: E-GEOD-63159 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA