Ontology highlight
ABSTRACT:
ORGANISM(S): Candida parapsilosis
SUBMITTER: Tristan Rossignol
PROVIDER: E-GEOD-6318 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Antimicrobial agents and chemotherapy 20070701 7
In Candida albicans, the quorum-sensing molecule farnesol inhibits the transition from yeast to hyphae but has no effect on cellular growth. We show that the addition of exogenous farnesol to cultures of Candida parapsilosis causes the cells to arrest, but not at a specific stage in the cell cycle. The cells are not susceptible to additional farnesol. However, the cells do eventually recover from arrest. Unlike in C. albicans, in C. parapsilosis sterols are localized to the tips of budding cells ...[more]