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Gene expression profiling of optic nerve from Tcf7l2 mutant and control mice

ABSTRACT: We performed gene expression pofiling of of optic nerve from Tcf7l2 mutant and control mice and identified significantly changed genes in mutant. RNA-seq of P12 optic nerve from control and mutant mice.

ORGANISM(S): Mus musculus

SUBMITTER: Richard Lu

PROVIDER: E-GEOD-65118 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling of optic nerve from Tcf7l2 mutant and control mice

Project description:We performed gene expression pofiling of of optic nerve from Tcf7l2 mutant and control mice and identified significantly changed genes in mutant.

2016-02-19 | GSE65118 | GEO

Chromatin occupancy and target genes of TCF7L2 in hepatocytes

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Project description:Genetic variants in TCF7L2 are the most highly associated variants with type 2 diabetes.We performed RNA_seq experiments on Control and Knockdown samples for 4 passages each. Library preparation was performed according to mRNA Sequening Sample Preparation Guide (illumina). Reagents were taken from the Illumina sample preparation kit v.2. Knockdown and control samples were sequenced together in one flowcell, 6 samples per lane. The aim of this study is to identify the downstream target genes that might the involvement of TCF7L2 in the development of type 2 diabetes. No technical replicate, 4 biological replicates.

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Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3

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2012-06-05 | E-GEOD-38447 | biostudies-arrayexpress

Mus musculus

Project description:Gene expression profiling of optic nerve from Tcf7l2 mutant and control mice

| PRJNA273065 | ENA

Bulk RNASeq of mouse astrocytes isolated from the somatosensory cortex of control and Tcf7l2 conditional knockout (TdTomato+).

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2024-06-28 | E-MTAB-13153 | biostudies-arrayexpress

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