Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Zhiying Ai
PROVIDER: E-GEOD-67570 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Stem cells international 20151207
Embryonic stem cells (ESCs) have the ability to grow indefinitely and retain their pluripotency in culture, and this self-renewal capacity is governed by several crucial molecular pathways controlled by specific regulatory genes and epigenetic modifications. It is reported that multiple epigenetic regulators, such as miRNA and pluripotency factors, can be tightly integrated into molecular pathways and cooperate to maintain self-renewal of ESCs. However, mouse ESCs in serum-containing medium seem ...[more]