Ontology highlight
ABSTRACT:
INSTRUMENT(S): G2565BA DNA microarray scanner [Agilent]
ORGANISM(S): Saccharomyces pastorianus
SUBMITTER: Satoshi Yoshida
PROVIDER: E-MEXP-1086 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Yoshida Satoshi S Imoto Jun J Minato Toshiko T Oouchi Rie R Sugihara Mao M Imai Takeo T Ishiguro Tatsuji T Mizutani Satoru S Tomita Masaru M Soga Tomoyoshi T Yoshimoto Hiroyuki H
Applied and environmental microbiology 20080229 9
Sulfite plays an important role in beer flavor stability. Although breeding of bottom-fermenting Saccharomyces strains that produce high levels of SO(2) is desirable, it is complicated by the fact that undesirable H(2)S is produced as an intermediate in the same pathway. Here, we report the development of a high-level SO(2)-producing bottom-fermenting yeast strain by integrated metabolome and transcriptome analysis. This analysis revealed that O-acetylhomoserine (OAH) is the rate-limiting factor ...[more]