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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of occipital cortex tissue from male and female humans, macaques and marmosets to investigate sex differences in primate brain

ABSTRACT: We compared gene expression patterns between the occipital cortex tissues of four male and four female individuals in three species: an ape (human, Homo sapiens), an Old World monkey (macaque; Macaca fascicularis), and a New World monkey (marmoset; Callithrix jacchus). To do so, we hybridized cDNA from each sample (n = 24) to a human cDNA microarray that contains 46,128 probes. (Human 46k cDNA, http://www.biotech.kth.se/molbio/microarray/). We used a loop hybridization study design restricted to within-species comparisons only, in which we co-hybridized on each slide samples from the opposite sex.

INSTRUMENT(S): GenePix 4000A [Axon Instruments]

ORGANISM(S): Callithrix jacchus

SUBMITTER: Björn Reinius

PROVIDER: E-MEXP-1182 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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