Transcription profiling of human peripheral blood mononuclear cells from radiation-exposed workers versus control subjects

ABSTRACT: We used peripheral blood mononuclear cells to study the gene expression profiles of radiation-exposed workers versus control subjects. Human PBMC were isolated from 56 healthy donors who were working in a local Hospital (Bologna, Italy): 28 individuals were x and g radiation-exposed workers, recruited from the Nuclear Medicine and Cardiovascular Units, while the control group consisted of 28 unexposed subjects, working at the same health care facility, matched for sex, age and smoking habits. The mean dosimeter reading, expressed as accumulated doses, during the entire time of employment (range: 1-32 years), was 19.49±37.59 mSv (mean ± SD). All procedures related to the collection of blood samples were performed with an informed consent and according to the protocol approved by the Institutional Review Board.

ORGANISM(S): Homo sapiens

SUBMITTER: Elena Morandi 

PROVIDER: E-MEXP-1277 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress