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Transcription profiling of human colon cancer cell line SW480 expressing ERb and then treated with estrogen or untreated

ABSTRACT: Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERb-mediated gene regulation in the SW480 colon cancer cell line. The colon cancer cell line SW480 does not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ERb expression cassette. Introduction of ERb makes it possible to study the role and function of ERb in colon cancer as well as the impact ERb has on its own (in the absence of ERa).

ORGANISM(S): Homo sapiens

SUBMITTER: Karin Edvardsson

PROVIDER: E-MEXP-1473 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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