Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling wild type C. albicans after treatment with stress-inducing doses of acetic acid

ABSTRACT: Transcript profiling was performed using a wild-type C. albicans strain (CaI8+CIp10). Cells were cultured in 50 ml SC-pH3.0 to a cell density of 1x10^7 cells per ml and then either treated with control (0 mM acetic acid) or stress inducing (20 mM acetic acid) doses. Cells from the same culture were harvested after 300 min treatment. Three independent biological replicates were obtained for each condition.

ORGANISM(S): Candida albicans

SUBMITTER: Mark Ramsdale 

PROVIDER: E-MEXP-1633 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans.

Ramsdale Mark M   Selway Laura L   Stead David D   Walker Jan J   Yin Zhikang Z   Nicholls Susan M SM   Crowe Jonathan J   Sheils Emma M EM   Brown Alistair J P AJ  

Molecular biology of the cell 20080723 10

MNL1, the Candida albicans homologue of an orphan Msn2-like gene (YER130c in Saccharomyces cerevisiae) has no known function. Here we report that MNL1 regulates weak acid stress responses. Deletion of MNL1 prevents the long-term adaptation of C. albicans cells to weak acid stresses and compromises their global transcriptional response under these conditions. The promoters of Mnl1-dependent genes contain a novel STRE-like element (SLE) that imposes Mnl1-dependent, weak acid stress-induced transcr  ...[more]

Similar Datasets

Transcriptomics Transcription profiling of Candida albicans wildtype and hsf1 mutant cells after heatstress
2009-12-17 | E-MEXP-2044 | biostudies-arrayexpress
Transcriptomics Transcription profiling by array of Candida albicans to compare Gcn4 and Gcn2 regulons
2010-05-13 | E-MEXP-1212 | biostudies-arrayexpress
Transcriptomics Transcription profiling by array of Candida albicans tup1, nrg1 and ssn6 mutants
2010-05-14 | E-MEXP-1217 | biostudies-arrayexpress
Transcriptomics Transcription profiling of Candida albicans clinical isolates grown under identical growth conditions in NGY medium
2009-02-11 | E-MEXP-1931 | biostudies-arrayexpress
Transcriptomics Transcription profiling of Candida albicans clinical isolates
2009-02-11 | E-MEXP-1933 | biostudies-arrayexpress
Transcriptomics Transcription profiling of wild type and hog1 Candida albicans subjected to environmental stresses that are known to activate the Hog1 Stress-activated Protein Kinase
2007-07-05 | E-MEXP-1134 | biostudies-arrayexpress
Transcriptomics Transcription profiling of Candida albicans in response to a sudden availability of glucose in the extracellular medium, having previously been grown on a non-fermentable carbon source
2008-06-01 | E-MEXP-1151 | biostudies-arrayexpress
Transcriptomics Transcription profiling of Candida albicans wild type strain BWP17 and mutant hac1 treated with DTT or tunicamycin to investigate the effect of the Unfolded Protein Response of genome-wide expression patterns
2008-06-11 | E-MEXP-1307 | biostudies-arrayexpress
Transcriptomics Transcription profiling time series of Candida albicans treated with different doses of acetic acid
2008-07-31 | E-MEXP-1645 | biostudies-arrayexpress
Transcriptomics Transcription profiling of Candida albicans wild type and mnl1 cells after treatment with acetic acid
2008-07-31 | E-MEXP-1641 | biostudies-arrayexpress