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Transcription profiling of intestine from mice infected with three isolates of Trichuris muris for 7 days to determine early changes in gene expression that may later determine the outcome of infection

ABSTRACT: Trichuris muris, the mouse whipworm is used as a laboratory model of the human parasite T. trichuira - a gastrointestinal nematode. Three laboratory isolates of T. muris exist: the E, J and S isolates. Previous data has shown that the S isolate survives to chronicity in C57BL/6 mice unlike the E and J isolates which are expelled. The ability of the S isolate to persist is still unclear. Microarray analysis of gut samples from mice infected with either the E or S isolates of T. muris for 7 days was used to determine early changes in gene expression that may later determine the outcome of infection.

ORGANISM(S): Mus musculus

SUBMITTER: Leo Zeef

PROVIDER: E-MEXP-1795 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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