Dataset Information
Transcription profiling of Drosophila wild type and Ada2b knockout L3 larvae synchronized to spiracle eversion
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Tibor Pankotai
PROVIDER: E-MEXP-2125 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Genes of the ecdysone biosynthesis pathway are regulated by the dATAC histone acetyltransferase complex in Drosophila.
Molecular and cellular biology 20100628 17
Uncovering mechanisms that regulate ecdysone production is an important step toward understanding the regulation of insect metamorphosis and processes in steroid-related pathologies. We report here the transcriptome analysis of Drosophila melanogaster dAda2a and dAda3 mutants, in which subunits of the ATAC acetyltransferase complex are affected. In agreement with the fact that these mutations lead to lethality at the start of metamorphosis, both the ecdysone levels and the ecdysone receptor bind ...[more]
