Unknown,Transcriptomics,Genomics,Proteomics

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MicroRNA profiling of human CD8 T cells - miR-17 and miR-19b to investigate down-regulatation in human aging


ABSTRACT: T cells from several blood donors were separated in populations corresponding to CD8+ CD28+ and CD8+ CD28- surface markers. Total RNA extracts from cells were hybridized to MRC LNA microarray. Contrasts of interest were CD8CD28- minus CD8CD28+ (replicative aging) and CD8CD28+ (old donors) minus CD8CD28+ (young donors), which corresponds to chronological aging.

ORGANISM(S): Homo sapiens

SUBMITTER: Matthias Hackl 

PROVIDER: E-MEXP-2398 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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