Ontology highlight
ABSTRACT:
ORGANISM(S): Burkholderia cenocepacia
SUBMITTER: Silvia Bazzini
PROVIDER: E-MEXP-2997 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20110419 4
Burkholderia cenocepacia J2315 is representative of a highly problematic group of cystic fibrosis (CF) pathogens. Eradication of B. cenocepacia is very difficult with the antimicrobial therapy being ineffective due to its high resistance to clinically relevant antimicrobial agents and disinfectants. RND (Resistance-Nodulation-Cell Division) efflux pumps are known to be among the mediators of multidrug resistance in gram-negative bacteria. Since the significance of the 16 RND efflux systems prese ...[more]