Dataset Information
Reproducibility M-Tram of Enterococcus faecium strain E1162
Ontology highlight
ABSTRACT:
ORGANISM(S): Enterococcus faecium
SUBMITTER: Xinglin Zhang
PROVIDER: E-MEXP-3502 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium.
PLoS genetics 20120628 6
Enterococcus faecium has become a nosocomial pathogen of major importance, causing infections that are difficult to treat owing to its multi-drug resistance. In particular, resistance to the β-lactam antibiotic ampicillin has become ubiquitous among clinical isolates. Mutations in the low-affinity penicillin binding protein PBP5 have previously been shown to be important for ampicillin resistance in E. faecium, but the existence of additional resistance determinants has been suggested. Here, we ...[more]
