Dataset Information
Comparison of gene transcription in Caco-2 cells stimulated with Lactobacillus salivarius UCC118 with that in unstimulated cells.
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: John O'Callaghan
PROVIDER: E-MEXP-3597 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Influence of adhesion and bacteriocin production by Lactobacillus salivarius on the intestinal epithelial cell transcriptional response.
Applied and environmental microbiology 20120518 15
Lactobacillus salivarius strain UCC118 is a human intestinal isolate that has been extensively studied for its potential probiotic effects in human and animal models. The objective of this study was to determine the effect of L. salivarius UCC118 on gene expression responses in the Caco-2 cell line to improve understanding of how the strain might modulate intestinal epithelial cell phenotypes. Exposure of Caco-2 cells to UCC118 led to the induction of several human genes (TNFAIP3, NFKBIA, and BI ...[more]
