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Transcription profiling of Caenorhabditis elegans ASEL and ASER taste neurons.

ABSTRACT: Comparison of the transcriptional profiles between ASEL and ASER neurons in C. elegans

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Jun Takayama

PROVIDER: E-MEXP-2412 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Single-cell transcriptional analysis of taste sensory neuron pair in Caenorhabditis elegans.

Takayama Jun J Faumont Serge S Kunitomo Hirofumi H Lockery Shawn R SR Iino Yuichi Y

Nucleic acids research 20091029 1

The nervous system is composed of a wide variety of neurons. A description of the transcriptional profiles of each neuron would yield enormous information about the molecular mechanisms that define morphological or functional characteristics. Here we show that RNA isolation from single neurons is feasible by using an optimized mRNA tagging method. This method extracts transcripts in the target cells by co-immunoprecipitation of the complexes of RNA and epitope-tagged poly(A) binding protein expr ...[more]

PMID: 19875417

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