CENAT-AML-experiment1

ABSTRACT: Acute myeloid leukemia (AML) is the most common and severe acute leukemia in adults. It is a heterogeneous disease where the subset of molecularly different types, presenting various morphological features and differentiation stage, can be distinguished. Genomic research of leukemias is conducted since 1999 and large cohort studies shown that particular genetic alterations correspond with specific gene expression signatures. However, not always they provide clinically relevant information. The most unknown group is cytogenetically normal acute myeloid leukemia (CN-AML, 40-49% of all AML cases). The aim of our experiment was to determine selected gene expression profiles in CN-AML, using small, boutique microarray. The array contained 933 oligonucleotide probes, mainly complementary to acut

ORGANISM(S): Homo sapiens

DISEASE(S): acute promyelocytic leukemia

SUBMITTER: Luiza Handschuh 

PROVIDER: E-MEXP-3647 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress