Sensitivity-resistance to the atypical retinoid ST1926 in NB4 acute myeloid leukemia cells

ABSTRACT: The two cell lines NB4 and NB4.437r, respectively sensitive and resistant to the cytotoxic action of the atypical retinoid ST1926 and CD437 were used to unveil the mechanism of action of these drugs.We compared their transcriptional profiles in conditions of exponential growth in basal medium by microarray gene expressio analysis.

ORGANISM(S): Homo sapiens

SUBMITTER: Maddalena Fratelli 

PROVIDER: E-MEXP-3752 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress