Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

61 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiR-126-126star in melanoma cell lines

ABSTRACT: Based on microRNA expression profiling studies, here we focus on miR-126&126* as the most downmodulated microRNAs in a panel of melanoma cell lines at different stages of progression compared with normal human melanocytes. At present no data exist on miR-126&126* possible role in melanoma. Our results show miR-126/miR-126* downregulation associated with tumor progression and the antineoplastic role deriving from their restored expression in metastatic melanomas in vitro as well as in vivo.

ORGANISM(S): Homo sapiens

SUBMITTER: nadia felli

PROVIDER: E-MEXP-3629 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling by array of rice plants following cold treatment

Project description:Wild-type rice plants (O. sativa L. cv. Nipponbare) were grown in plastic pots filled with nutrient soil for 2 weeks under flooded lowland conditions and a 12 h/12 h light/dark cycle (50 M-1 10 ?mol photons/m2/s) at 28M-0C (day) and 25M-0C (night). For cold treatment, two-week-old plants were transferred from 28M-0C to 10M-0C and incubated for 1 day.

2011-05-20 | E-MEXP-2725 | biostudies-arrayexpress

OsPIF1_OX_Node

Project description:Total RNA was isolated with RNAiso regent (Takara) from node portions at a heading stage of transgenic rice (Oryza sativa L. cv. Nipponbare) plants overexpressing OsPIF1 and vector control plants grown in green house at 28 C (day) and 25 C (night) under natural light conditions supplemented with metal halide lamps to provide 14-h daylength.

2012-09-28 | E-MEXP-3605 | biostudies-arrayexpress

Transcription profiling of Arabidopsis thalianawild type and areb1 areb2 abf3 triple mutant seedlins after 6h of dehydration

Project description:Total RNA was isolated with RNAiso regent (Takara) from 12-day-old seedlings of the areb1 areb2 abf3 triple mutant and WT plants grown on GM agar plates with stress treatment of dehydration for 6 h.

2010-08-04 | E-MEXP-2294 | biostudies-arrayexpress

grf7-1

Project description:Arabidopsis thaliana (L.) Heynh. ecotype Columbia was used in this study. Seeds were sterilized and stratified at 4 C for 2 days in the dark, sown, and grown on germination media (GM) agar plates in a growth chamber with 16 hours of fluorescent light at 40M-110 ?mol m-2 sec-1, 22 C, and 70% relative humidity. The T-DNA insertion line for GRF7 was obtained from the ABRC (Stock No. CS878963;? Sessions et al., 2002). The T-DNA insertion was confirmed by amplifying the LB-flanking region in genomic DNA of individual candidate lines.

2013-02-12 | E-MEXP-3559 | biostudies-arrayexpress

Expression of microRNAs and their target mRNAs in hESC-derived cardiomyocyte clusters and in heart tissue_microRNA_data

Project description:Parallel transcription profiling of cardiomyocyte clusters derived from human embryonic stem cells. Both mRNA (E-MEXP-2654) and miRNA (this experiment) transcription are measured and fetal and adult heart tissues are included as controls. This experiment was updated on 7th July 2011 to fix incorrect AH6 and FH3 files

2011-03-30 | E-MEXP-2655 | biostudies-arrayexpress

MicroRNA profiling of human prostate cancer

Project description:miRNA expression profiling of 13 clinical prostate samples, 4 benign prostate hyperplasias, 5 untreated primary prostate carcinomas and 4 castration-resistant prostate cancers.

2010-01-31 | E-MEXP-2319 | biostudies-arrayexpress

Transcription profiling by array of mouse BALB/c3T3 cell lines exposed to low or high irradiation doses

Project description:We used the BALB/c3T3 cell line model to correlate citotoxicity and transformation endpoints to expression gene profiles after IR exposure. Citotoxicity and Cell Transformation Assay (CTA) were performed 20h after IR exposure by using BALB/c3T3 cells. At the same time, RNAs of exposed cells to a low dose (0.25Gy) and to a high dose (3Gy) were extracted for microarray experiments.

2010-12-15 | E-MEXP-2830 | biostudies-arrayexpress

Virant-klun _SSEA-4-positive Cells Isolated from Adult Human Ovarian Cell Cultures

Project description:Comparison of gene expression profile of different types of cells: hESCs (H1), human adult dermal fibroblasts, cells from adult human ovarian cell culture, FACS sorted SSEA-4 positive cells from adult human ovarian culture and cells from human ovarian cancer cell culture.

2014-05-03 | E-MEXP-3774 | biostudies-arrayexpress

Genomic profiling of high-risk diffuse large B-cell lymphoma patients treated with dose-dense chemoimmunotherapy

Project description:The aim of the study was to identify molecular mechanisms involved in high risk diffuse large B-cell lymphomas (diffuse large B-cell lymphomas). 51 prospectively collected tumor samples from the patients treated in the Nordic phase II study with dose-dense chemoimmunotherapy followed by systemic CNS prophylaxis were analyzed by high resolution array comparative genomic hybridization (aCGH). The aCGH data were combined with the transcriptomics information from the exon array and the data associated with survival.

2012-03-30 | E-MEXP-3463 | biostudies-arrayexpress

Downstream analysis of DREB2A and DREB2B

Project description:Transcriptome analysis of transgenic Arabidopsis overexpressing a constitutive active form of DREB2A or DREB2B

2023-12-30 | E-MEXP-3606 | biostudies-arrayexpress