Dataset Information
Comparative genomic hybridization to map an amplified region in 1q23 in human sarcomas
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Agilent G2565BA
ORGANISM(S): Homo sapiens
DISEASE(S): malignant fibrous histiocytoma
SUBMITTER: Wen-Lin Kuo
PROVIDER: E-MEXP-427 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH.
Molecular cancer 20051107
<h4>Background</h4>Amplification of the q21-q23 region on chromosome 1 is frequently found in sarcomas and a variety of other solid tumours. Previous analyses of sarcomas have indicated the presence of at least two separate amplicons within this region, one located in 1q21 and one located near the apolipoprotein A-II (APOA2) gene in 1q23. In this study we have mapped and characterized the amplicon in 1q23 in more detail.<h4>Results</h4>We have used fluorescence in situ hybridisation (FISH) and m ...[more]
