Dataset Information
Comparative genomic hybridization of human leiomyosarcomas and gastrointestinal stromal tumors
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Agilent G2565BA
ORGANISM(S): Homo sapiens
DISEASE(S): Leiomyosarcoma
SUBMITTER: Heidi Namløs
PROVIDER: E-MEXP-707 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas.
Cancer research 20060901 18
Leiomyosarcomas are spindle cell tumors showing smooth muscle differentiation. Until recently, most gastrointestinal stromal tumors (GIST) were also classified as smooth muscle tumors, but now GISTs are recognized as a separate entity, defined as spindle cell and/or epithelioid tumors localized in the gastrointestinal tract. Using microarray-based comparative genomic hybridization (array CGH), we have created a detailed map of DNA copy number changes for 7 GISTs and 12 leiomyosarcomas. Considera ...[more]
