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Antibody arrays for identification of biomarkers of Immunoglobulin A nephropathy


ABSTRACT: Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis worldwide. However, biomarkers for predicting the progression or regression of IgAN remain a clinical challenge. In the present study, we aim to identify novel diagnostic and prognostic markers of IgAN. Using the cytokine antibody array, we detected serum and urinary levels of nine potential IgAN biomarkers in 32 IgAN patients and 16 healthy controls. The IgAN patients were grouped according to Lee’s grading system, with 16 patients with Grade I–II in the mild IgAN group and 16 with Grade III-V in the severe IgAN group. The associations between levels of these markers and IgAN were evaluated.

ORGANISM(S): Homo sapiens

SUBMITTER: Wenjun Zhao 

PROVIDER: E-MTAB-11972 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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