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CDNA microarray expression data from human aortic smooth muscle cells compared for 9p21.3 coronary artery disease risk locus genotypes

ABSTRACT: The 9p21.3 genetic locus is a well-established risk factor for coronary artery disease (CAD), however there is much about its exact mechanism that is yet to be established. To explore the impact of the 9p21.3 CAD risk locus on gene expression within a pathologically relevant cell type the transcriptome profiles of 9p21.3 homozygous risk (HR), heterozygous (HET) and homozygous non-risk (HNR) genotypes were determined in primary human aortic smooth muscle cells (HAoSMC). Total RNA was isolated from 4 HR, 4 HET and 3 HNR primary cells and gene expression quantified using the Affymetrix Human Gene 1.0 ST array.

ORGANISM(S): Homo sapiens

SUBMITTER: Ragnar Vilmundarson

PROVIDER: E-MTAB-12709 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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