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Primary peripheral T-cell lymphoma, not otherwise specified of the thyroid with autoimmune thyroiditis

ABSTRACT: Comprehensive gene expression profiles of four Primary T-cell lymphomas of the thyroid were analyzed to detect tumor-specific genes. The gene expression profiles of CD4 positive T-lymphocytes from normal donor were analyzed as control samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Noriaki Yoshida

PROVIDER: E-MTAB-1411 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Primary peripheral T-cell lymphoma, not otherwise specified of the thyroid with autoimmune thyroiditis.

Yoshida Noriaki N Nishikori Momoko M Izumi Tohru T Imaizumi Yoshitaka Y Sawayama Yasushi Y Niino Daisuke D Tashima Masaharu M Hoshi Sayuri S Ohshima Koichi K Shimoyama Masanori M Seto Masao M Tsukasaki Kunihiro K

British journal of haematology 20130221 2

Primary peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) of the thyroid is an extremely rare neoplasm. Six cases of primary PTCL-NOS of the thyroid were analysed for clinicopathological features and genomic alteration patterns using oligo-array comparative genomic hybridization. All patients had a diffusely enlarged thyroid and three cases showed leukaemic manifestation. Five of the six cases had anti-thyroid antibodies and the remaining case showed hypothyroidism, suggesting that ...[more]

PMID: 23432459

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