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Transcription profiling of Corynebacterium glutamicum grown in fermenter at different pH values.

ABSTRACT: Analysis of the transcriptomes of cell grown at different pH levels pH6.0, pH7.5, pH9.0; Cells were grown in a fermenter at different pH values to an oD600 between 4.5 to 11.5

ORGANISM(S): Corynebacterium glutamicum

SUBMITTER: Christian Rückert

PROVIDER: E-MTAB-151 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis.

Follmann Martin M Ochrombel Ines I Krämer Reinhard R Trötschel Christian C Poetsch Ansgar A Rückert Christian C Hüser Andrea A Persicke Marcus M Seiferling Dominic D Kalinowski Jörn J Marin Kay K

BMC genomics 20091221

<h4>Background</h4>The maintenance of internal pH in bacterial cells is challenged by natural stress conditions, during host infection or in biotechnological production processes. Comprehensive transcriptomic and proteomic analyses has been conducted in several bacterial model systems, yet questions remain as to the mechanisms of pH homeostasis.<h4>Results</h4>Here we present the comprehensive analysis of pH homeostasis in C. glutamicum, a bacterium of industrial importance. At pH values between ...[more]

PMID: 20025733

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