Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling by array for comparison of industrial Escherichia coli strains on growth, transcriptome and proteome level in batch cultivations to identify strain specific features (subexperiment K-12 platform)


ABSTRACT: The objective of the current study was to evaluate the performance of frequently used E. coli K-12 strains HMS174 and RV308 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied transcriptome analysis to interpret phenotypic attributes at the molecular level. The resulting enhancement of knowledge about host physiology is expected to contribute to the acceleration of improvements and optimizations in related biotech processes.

ORGANISM(S): Escherichia coli

SUBMITTER: Peter Krempl 

PROVIDER: E-MARS-20 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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