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MicroRNA and piRNA profiles in normal human testis

ABSTRACT: We employed Solexa sequencing technology to profile miRNAs and piRNA in normal human testis, three cases, pulled together

INSTRUMENT(S): Illumina Genome Analyzer II

ORGANISM(S): Homo sapiens

SUBMITTER: Yuanwei Zhang

PROVIDER: E-MTAB-1629 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MicroRNA and piRNA profiles in normal human testis detected by next generation sequencing.

Yang Qingling Q Hua Juan J Wang Liu L Xu Bo B Zhang Huan H Ye Nan N Zhang Zhiqiang Z Yu Dexin D Cooke Howard J HJ Zhang Yuanwei Y Shi Qinghua Q

PloS one 20130624 6

<h4>Background</h4>MicroRNAs (miRNAs) are the class of small endogenous RNAs that play an important regulatory role in cells by negatively affecting gene expression at transcriptional and post-transcriptional levels. There have been extensive studies aiming to discover miRNAs and to analyze their functions in the cells from a variety of species. However, there are no published studies of miRNA profiles in human testis using next generation sequencing (NGS) technology.<h4>Results</h4>We employed ...[more]

PMID: 23826142

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