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Transcription profiling of mouse myotubes infected with PGCalpha

ABSTRACT: Various studies have shown that aerobic exercise can prevent or alleviate cancer-induced muscle wasting. To reproduce at least partially in vitro some molecular differences of aerobic muscle exercise that are independent from systemic inflammation or the hormonal milieu, we infected fully differentiated myotubes with adenoviruses expressing PGC1α, one of the main transcriptional coactivators involved in muscle adaptation to endurance exercise. We then compared the effect of PGC1α expression at 48h in myotubes infected with GFP, used as control.

ORGANISM(S): Mus musculus

SUBMITTER: Luca Beltrame

PROVIDER: E-MTAB-8457 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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