Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Caroline Feig
PROVIDER: E-TABM-234 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Human reproduction (Oxford, England) 20071006 11
<h4>Background</h4>The molecular basis of human testicular dysfunction is largely unknown. Global gene expression profiling of testicular biopsies might reveal an expression signature of spermatogenic failure in azoospermic men.<h4>Methods</h4>Sixty-nine individual testicular biopsy samples were analysed on two microarray platforms; selected genes were validated by quantitative real-time PCR and immunohistochemistry.<h4>Results</h4>A minimum of 188 transcripts were significantly increased on bot ...[more]