Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC10469582 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Li Yijia Y Moser Carlee C Aga Evgenia E Currier Judith S JS Wohl David A DA Daar Eric S ES Ritz Justin J Greninger Alexander L AL Sieg Scott S Parikh Urvi M UM Coombs Robert W RW Hughes Michael D MD Eron Joseph J JJ Smith Davey M DM Chew Kara W KW Li Jonathan Z JZ
The Journal of infectious diseases 20230801 Suppl 2
Immunocompromised individuals are disproportionately affected by severe coronavirus disease 2019, but immune compromise is heterogenous, and viral dynamics may vary by the degree of immunosuppression. In this study, we categorized ACTIV-2/A5401 participants based on the extent of immunocompromise into none, mild, moderate, and severe immunocompromise. Moderate/severe immunocompromise was associated with higher nasal viral load at enrollment (adjusted difference in means: 0.47 95% confidence inte ...[more]