Establishing a Mouse Model for Sexual Transmission and Male Reproductive Tract Persistence of Ebola virus.
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ABSTRACT:
SUBMITTER: Clancy CS
PROVIDER: S-EPMC10651199 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
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Establishing a Mouse Model for Sexual Transmission and Male Reproductive Tract Persistence of Ebola Virus.
Clancy Chad S CS Smart Gabrielle G Rhoderick J Fred JF O'Donnell Kyle L KL Rosenke Rebecca R Schäfer Alexandra A Marzi Andrea A
The Journal of infectious diseases 20231101 Suppl 7
Ebola virus disease (EVD) has resulted in the death of over 15 000 people since its discovery in 1976. At least 1 incident of re-emergence of EVD has been associated with persistent male reproductive tract infection in a patient surviving EVD greater than 500 days prior. To date, animal models of Ebola virus (EBOV) infection have failed to fully characterize the pathogenesis of reproductive tract infection. Furthermore, no animal model of sexual transmission of EBOV exists. In this study, we des ...[more]
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