Ontology highlight
ABSTRACT:
SUBMITTER: Pol A
PROVIDER: S-EPMC1073686 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Pol Albert A Martin Sally S Fernández Manuel A MA Ingelmo-Torres Mercedes M Ferguson Charles C Enrich Carlos C Parton Robert G RG
Molecular biology of the cell 20050202 4
Caveolins are a crucial component of plasma membrane (PM) caveolae but have also been localized to intracellular compartments, including the Golgi complex and lipid bodies. Mutant caveolins associated with human disease show aberrant trafficking to the PM and Golgi accumulation. We now show that the Golgi pool of mainly newly synthesized protein is detergent-soluble and predominantly in a monomeric state, in contrast to the surface pool. Caveolin at the PM is not recognized by specific caveolin ...[more]