Ontology highlight
ABSTRACT:
SUBMITTER: Jenner RG
PROVIDER: S-EPMC113985 | biostudies-literature | 2001 Jan
REPOSITORIES: biostudies-literature
Jenner R G RG Albà M M MM Boshoff C C Kellam P P
Journal of virology 20010101 2
Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8) is associated with three human tumors, Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman's disease. KSHV encodes a number of homologs of cellular proteins involved in the cell cycle, signal transduction, and modulation of the host immune response. Of the virus complement of over 85 open reading frames (ORFs), the expression of only a minority has been characterized individually. We have constructed a ...[more]