Ontology highlight
ABSTRACT:
SUBMITTER: Huang LS
PROVIDER: S-EPMC1540442 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Huang Li Shar LS Borders Toni M TM Shen John T JT Wang Chung Jen CJ Berry Edward A EA
Acta crystallographica. Section D, Biological crystallography 20050324 Pt 4
A procedure is presented for preparation of diffraction-quality crystals of a vertebrate mitochondrial respiratory complex II. The crystals have the potential to diffract to at least 2.0 A with optimization of post-crystal-growth treatment and cryoprotection. This should allow determination of the structure of this important and medically relevant membrane-protein complex at near-atomic resolution and provide great detail of the mode of binding of substrates and inhibitors at the two substrate-b ...[more]