Ontology highlight
ABSTRACT:
SUBMITTER: Albrecht R
PROVIDER: S-EPMC1794701 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Albrecht Reinhard R Rehling Peter P Chacinska Agnieszka A Brix Jan J Cadamuro Sergio A SA Volkmer Rudolf R Guiard Bernard B Pfanner Nikolaus N Zeth Kornelius K
EMBO reports 20061110 12
Proteins destined for the mitochondrial matrix are imported by the translocase of the outer membrane--the TOM complex--and the presequence translocase of the inner membrane--the TIM23 complex. At present, there is no structural information on components of the presequence translocase. Tim21, a subunit of the presequence translocase consisting of a membrane anchor and a carboxy-terminal domain exposed to the intermembrane space, directly connects the TOM and TIM23 complexes by binding to the inte ...[more]