Ontology highlight
ABSTRACT:
SUBMITTER: Lemay JF
PROVIDER: S-EPMC1800517 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Lemay Jean-François JF Lafontaine Daniel A DA
RNA (New York, N.Y.) 20070102 3
The adenine riboswitch aptamer, the A box, positively regulates gene expression upon adenine binding. To provide insight into structure-function relationships, important for the adenine riboswitch aptamer, we have created alignments for six aptamer sequences that reveal the core requirements. In addition, 2-aminopurine (2AP) binding studies have been used to test the consensus sequence derived from the alignment. Overall, the consensus secondary structure is consistent with 2AP binding studies. ...[more]