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Novel base catalysed rearrangement of sultone oximes to 1,2-benzisoxazole-3-methane sulfonate derivatives.

ABSTRACT: A new process for the preparation of 1,2-benzisoxazole-3-methanesulfonates and 4-oximino-2,3-dihydrobenzoxathiin-2,2-dioxides (sultone oximes) is described. These compounds are important intermediates for the preparation of zonisamide, an anti-convulsant drug.

SUBMITTER: Arava VR

PROVIDER: S-EPMC1919382 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature

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Novel base catalysed rearrangement of sultone oximes to 1,2-benzisoxazole-3-methane sulfonate derivatives.

Arava Veera Reddy VR Siripalli Udaya Bhaskara Rao UB Nadkarni Vaishali V Chinnapillai Rajendiran R

Beilstein journal of organic chemistry 20070608

A new process for the preparation of 1,2-benzisoxazole-3-methanesulfonates and 4-oximino-2,3-dihydrobenzoxathiin-2,2-dioxides (sultone oximes) is described. These compounds are important intermediates for the preparation of zonisamide, an anti-convulsant drug. ...[more]

PMID: 17555607

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