Ontology highlight
ABSTRACT:
SUBMITTER: Arthur CP
PROVIDER: S-EPMC1950735 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Arthur Christopher P CP Stowell Michael H B MH
Structure (London, England : 1993) 20070601 6
Synaptophysin I (SypI) is an archetypal member of the MARVEL-domain family of integral membrane proteins and one of the first synaptic vesicle proteins to be identified and cloned. Most all MARVEL-domain proteins are involved in membrane apposition and vesicle-trafficking events, but their precise role in these processes is unclear. We have purified mammalian SypI and determined its three-dimensional (3D) structure by using electron microscopy and single-particle 3D reconstruction. The hexameric ...[more]