Ontology highlight
ABSTRACT:
SUBMITTER: Lu Y
PROVIDER: S-EPMC2052923 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Lu Yun Y Thomson J Michael JM Wong Ho Yuen Frank HY Hammond Scott M SM Hogan Brigid L M BL
Developmental biology 20070809 2
The miR-17-92 locus encodes a cluster of 7 microRNAs transcribed as a single primary transcript. It can accelerate c-Myc induced B cell lymphoma development and is highly expressed in many tumors, including lung tumors. However, the role of miR-17-92 in development has not been well studied. From analysis of microRNAs during lung development, expression of the miR-17-92 cluster is high at early stages, but declines as development proceeds. We used the mouse surfactant protein C (Sftpc) promoter ...[more]