Ontology highlight
ABSTRACT:
SUBMITTER: Alvi A
PROVIDER: S-EPMC2168557 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Alvi Ayesha A Devi S Manjulata SM Ahmed Irshad I Hussain M Abid MA Rizwan Mohammed M Lamouliatte Hérve H Mégraud Francis F Ahmed Niyaz N
Journal of clinical microbiology 20071017 12
Helicobacter pylori cagA and vacA genotypes have been used for almost a decade as stable entities to link the severity of gastritis and ulcer disease. We describe here microevolution of the two genomic islands, cag pathogenicity island (cagPAI; 40 kb) and tfs3 (16 kb) from isolates obtained at inclusion (one subclone) and after a 10-year period (two subclones) from a duodenal ulcer patient. Our results indicate microevolution in cagA, cagE, and cag7 genes of the cagPAI and open reading frames G, ...[more]