Ontology highlight
ABSTRACT:
SUBMITTER: So M
PROVIDER: S-EPMC2323599 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
So Minjeong M Hvastkovs Eli G EG Schenkman John B JB Rusling James F JF
Biosensors & bioelectronics 20070728 4
Simultaneous optical and voltammetric detection of bioactivated genotoxicity is reported for the first time employing ultrathin films of DNA, model metabolic enzymes, and electrochemiluminescence (ECL) generating metallopolymer [Ru(bpy)2PVP10]2+ on pyrolytic graphite (PG) electrodes. Cytochrome P450cam and myoglobin were used as model monoxygenase enzymes to mimic in vivo processes. Sensor film growth and component amounts were monitored using a quartz crystal microbalance (QCM). Subsequent to t ...[more]