Ontology highlight
ABSTRACT:
SUBMITTER: Va P
PROVIDER: S-EPMC2538580 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Va Porino P Roush William R WR
Journal of the American Chemical Society 20061201 50
A convergent and highly stereocontrolled synthesis of amphidinolide E (1) has been accomplished. The synthesis features a highly diastereoselective (>20:1) BF3.Et2O promoted [3+2] annulation reaction between aldehyde 3 and allylsilane 4 to afford substituted tetrahydrofuran 2. ...[more]