Ontology highlight
ABSTRACT:
SUBMITTER: Morris JS
PROVIDER: S-EPMC2659628 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Morris Jeffrey S JS Brown Philip J PJ Herrick Richard C RC Baggerly Keith A KA Coombes Kevin R KR
Biometrics 20070920 2
In this article, we apply the recently developed Bayesian wavelet-based functional mixed model methodology to analyze MALDI-TOF mass spectrometry proteomic data. By modeling mass spectra as functions, this approach avoids reliance on peak detection methods. The flexibility of this framework in modeling nonparametric fixed and random effect functions enables it to model the effects of multiple factors simultaneously, allowing one to perform inference on multiple factors of interest using the same ...[more]