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Protein-functionalized synthetic antiferromagnetic nanoparticles for biomolecule detection and magnetic manipulation.

ABSTRACT: Direct protein functionalization provides synthetic antiferromagnetic nanoparticles with high chemical specificity and multifunctionality. These nanoparticle-protein conjugates function as improved magnetic labels for biological detection experiments, and exhibit tunable responses to a small external magnetic field gradient, thus allowing the observation of distinctive single nanoparticle motion.

SUBMITTER: Fu A

PROVIDER: S-EPMC2665302 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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Protein-functionalized synthetic antiferromagnetic nanoparticles for biomolecule detection and magnetic manipulation.

Fu Aihua A Hu Wei W Xu Liang L Wilson Robert J RJ Yu Heng H Osterfeld Sebastian J SJ Gambhir Sanjiv S SS Wang Shan X SX

Angewandte Chemie (International ed. in English) 20090101 9

Direct protein functionalization provides synthetic antiferromagnetic nanoparticles with high chemical specificity and multifunctionality. These nanoparticle-protein conjugates function as improved magnetic labels for biological detection experiments, and exhibit tunable responses to a small external magnetic field gradient, thus allowing the observation of distinctive single nanoparticle motion. ...[more]

PMID: 19156803

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