Ontology highlight
ABSTRACT:
SUBMITTER: Weedon MN
PROVIDER: S-EPMC2681221 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Nature genetics 20080406 5
Adult height is a model polygenic trait, but there has been limited success in identifying the genes underlying its normal variation. To identify genetic variants influencing adult human height, we used genome-wide association data from 13,665 individuals and genotyped 39 variants in an additional 16,482 samples. We identified 20 variants associated with adult height (P < 5 x 10(-7), with 10 reaching P < 1 x 10(-10)). Combined, the 20 SNPs explain approximately 3% of height variation, with a app ...[more]