Ontology highlight
ABSTRACT:
SUBMITTER: Hong YS
PROVIDER: S-EPMC2694382 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Hong Young Seoub YS Roh Mee Sook MS Kim Na Young NY Lee Hye Jung HJ Kim Hee Kyoung HK Lee Kyung Eun KE Kwak Jong Young JY Kim Joon Youn JY
Journal of Korean medical science 20070901
Promoter hypermethylation of the p16(INK4a) gene was investigated in 81 sets of samples of tumor tissue and adjacent normal tissue from Korean patients with primary lung cancer, using the modified real-time polymerase chain reaction (PCR)/ SYBR Green detection method. The results showed hypermethylation of p16(INK4a) in 27.2% of tumor tissues, and in 11.1% of adjacent normal tissue. No significant association was found between the overall aberrant methylation in tumor and corresponding normal sp ...[more]