Ontology highlight
ABSTRACT:
SUBMITTER: Arthur PK
PROVIDER: S-EPMC2740424 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20090520 30
Directional transport of specific mRNAs is of primary biological relevance. In Xenopus oocytes, mRNA localization to the vegetal pole is important for germ layer formation and germ cell development. Using a biochemical approach, we identified Xenopus Elr-type proteins, homologs of the Hu/ELAV proteins, as novel components of the vegetal mRNA localization machinery. They bind specifically to the localization elements of several different vegetally localizing Xenopus mRNAs, and they are part of on ...[more]