Dataset Information
Nickel-catalyzed cycloadditive couplings of enynes and isocyanates.
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ABSTRACT:
SUBMITTER: D'Souza BR
PROVIDER: S-EPMC2792207 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
Nickel-catalyzed cycloadditive couplings of enynes and isocyanates.
Organic letters 20090901 18
A mild and general route for preparing dienamides is described. Nickel imidazolylidene complexes were used to mediate cycloadditive coupling between enynes and isocyanates. Dienamides were prepared in excellent yields and with good E:Z selectivity. These dienamides can be further manipulated through oxidative cyclization methods. When a terminal enyne is employed, cyclization affords a lactam rather than a dienamide. ...[more]