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Catalytic enantioselective formation of chiral-bridged dienes which are themselves ligands for enantioselective catalysis.

ABSTRACT: This paper reports a method for highly enantioselective Diels-Alder reaction with an acetylene equivalent to produce chiral-bridged dienes. These dienes, by coordination to Rh(I), can serve as catalysts for the enantioselective addition of vinyl or aryl groups to alpha,beta-unsaturated ketones.

SUBMITTER: Brown MK

PROVIDER: S-EPMC2814301 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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Catalytic enantioselective formation of chiral-bridged dienes which are themselves ligands for enantioselective catalysis.

Brown M Kevin MK Corey E J EJ

Organic letters 20100101 1

This paper reports a method for highly enantioselective Diels-Alder reaction with an acetylene equivalent to produce chiral-bridged dienes. These dienes, by coordination to Rh(I), can serve as catalysts for the enantioselective addition of vinyl or aryl groups to alpha,beta-unsaturated ketones. ...[more]

PMID: 19947622

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